The tTA atlas is an interactive resource providing access to brain wide histological images displaying the distribution patterns of promoter activity in different tetracycline transactivator (tTA) mouse models


Michael J. Yetman1, Joanna L. Jankowsky2
The Jankowsky Lab
Departments of Neuroscience, Neurology, and Neurosurgery1, Huffington Center on Aging1,2, Baylor College of Medicine
Houston, TX
Sveinung Lillehaug, Jan G. Bjaalie, Trygve B. Leergaard
Neural Systems and Graphics Computing Laboratory
Institute of Basic Medical Sciences - Anatomy
University of Oslo
P.O. Box 1105 Blindern
N - 0317 Oslo



The atlas contains histological data documenting the activity of the Nop-tTA promoter in bigenic mice in which the Nop-tTA promoter regulates the expression of the LacZ reporter gene, encoding the histologically detectible marker β-galactosidase.

The Virtual Microscope tool allows users to navigate within and across section images.

The atlas is based on data from the following publication:

Yetman MJ, Lillehaug S, Bjaalie JG, Leergaard TB, Jankowsky JL (2015), Transgene expression in the Nop-TTA driver line is not inherently restricted to the entorhinal cortex. Brain Struct Funct DOI 10.1007/s00429-015-1040-9 (accepted manuscript)

Re-use of data from this repository is permitted provided reference is made to this publication. For methodological details, cfr. Yetman et al. (2015).